2012年12月19日，ECHA在其官网上正式公布第8批54项SVHC。截止目前，SVHC候选物清单中物质已达138种。
成员国委员会（MSC）一致确认了其中23项的分类。并首次确认3种呼吸致敏物，危险等级与致癌、致畸形和生殖毒性（CMRs）相当。
列入候选物质清单之列的54个物质如下：
|
序号 |
物质名称 |
EC号 |
CAS号 |
物质分类 |
|
1 |
3-ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine 3-乙基-2-甲基-2-(3-甲基丁基)噁唑烷 |
421-150-7 |
14 |
CMR1 |
|
2 |
4-methyl-m-phenylenediamine (2,4-toluene-diamine) 2,4-二氨基甲苯 |
202-453-1 |
95-80-7 |
CMR |
|
3 |
N-methylacetamide N-甲基乙酰胺 |
201-182-6 |
79-16-3 |
CMR |
|
4 |
Pentalead tetraoxide sulphate 氧化铅与硫酸铅的复合物 |
235-067-7 |
12065-90-6 |
CMR |
|
5 |
Biphenyl-4-ylamine 4-氨基联苯 |
202-177-1 |
92-67-1 |
CMR |
|
6 |
Dinoseb 地乐酚 |
201-861-7 |
88-85-7 |
CMR |
|
7 |
Dioxobis(stearato)trilead 双(十八酸基)二氧代三铅 |
235-702-8 |
12578-12-0 |
CMR |
|
8 |
Lead dinitrate 硝酸铅 |
233-245-9 |
10099-74-8 |
CMR |
|
9 |
Tetralead trioxide sulphate 三碱式硫酸铅 |
235-380-9 |
12202-17-4 |
CMR |
|
10 |
Lead oxide (lead monoxide) 氧化铅 |
215-267-0 |
1317-36-8 |
CMR |
|
11 |
Lead titanium trioxide 钛酸铅 |
235-038-9 |
12060-00-3 |
CMR |
|
12 |
4,4'-methylenedi-o-toluidine 4,4'-二氨基-3,3'-二甲基二苯甲烷 |
212-658-8 |
838-88-0 |
CMR |
|
13 |
Acetic acid, lead salt, basic 碱式乙酸铅 |
257-175-3 |
51404-69-4 |
CMR |
|
14 |
Dimethyl sulphate 硫酸二甲酯 |
201-058-1 |
77-78-1 |
CMR |
|
15 |
Furan 呋喃 |
203-727-3 |
110-00-9 |
CMR |
|
16 |
Pyrochlore, antimony lead yellow 颜料黄41 |
232-382-1 |
8012-00-8 |
CMR |
|
17 |
Tetraethyllead 四乙基铅 |
201-075-4 |
78-00-2 |
CMR |
|
18 |
Dibasic lead phthalate (phthalate(2-dioxotrilead)) 二盐基邻苯二甲酸铅 |
273-688-5 |
6 |
CMR |
|
19 |
Diethyl sulphate 硫酸二乙酯 |
200-589-6 |
64-67-5 |
CMR |
|
20 |
Lead cynamidate 氨基氰铅盐 |
244-073-9 |
20837-86-9 |
CMR |
|
21 |
Silicic acid, barium salt, lead-doped |
272-271-5 |
68784-75-8 |
CMR |
|
22 |
Trilead dioxide phosphonate 磷酸氧化铅 |
235-252-2 |
12141-20-7 |
CMR |
|
23 |
o-Toluidine; 2-Aminotoluene 邻甲基苯胺 |
202-429-0 |
95-53-4 |
CMR |
|
24 |
o-aminoazotoluene 邻氨基偶氮甲苯 |
202-591-2 |
97-56-3 |
CMR |
|
25 |
4-Aminoazobenzene; 4-Phenylazoaniline 对氨基偶氮苯 |
200-453-6 |
|
CMR |
|
26 |
6-methoxy-m-toluidine (p-cresidine) 2-甲氧基-5-甲基苯胺 |
204-419-1 |
120-71-8 |
CMR |
|
27 |
Dibutyltin dichloride (DBT) 二丁基锡 |
211-670-0 |
683-18-1 |
CMR |
|
28 |
Lead Titanium Zirconium Oxide 钛酸铅锆 |
235-727-4 |
12626-81-2 |
CMR |
|
29 |
Propylene oxide; 1,2-epoxypropane; methyloxirane 环氧丙烷 |
200-879-2 |
75-56-9 |
CMR |
|
30 |
1-bromopropane 溴代正丙烷 |
203-445-0 |
106-94-5 |
CMR |
|
31 |
Basic lead carbonate (trilead bis(carbonate)dihydroxide) 碱式碳酸铅 |
215-290-6 |
1319-46-6 |
CMR |
|
32 |
Fatty acids, C16-18, lead salts C16-18-脂肪酸铅盐 |
292-966-7 |
91031-62-8 |
CMR |
|
33 |
Lead tetroxide (orange lead) 四氧化三铅 |
215-235-6 |
1314-41-6 |
CMR |
|
34 |
Sulfurous acid, lead salt, dibasic 亚硫酸铅（II） |
263-467-1 |
6 |
CMR |
|
35 |
4,4'-oxydianiline and its salts 4,4'-二氨基二苯醚 |
202-977-0 |
101-80-4 |
CMR |
|
36 |
Basic lead sulphate (lead oxide sulphate) 碱式硫酸铅 |
234-853-7 |
12036-76-9 |
CMR |
|
37 |
Lead bis(tetrafluoroborate) 氟硼酸铅 |
237-486-0 |
13814-96-6 |
CMR |
|
38 |
Silicic acid, lead salt 硅酸铅 |
234-363-3 |
11120-22-2 |
CMR |
|
39 |
十溴联苯醚 Bis(pentabromophenyl) ether (DecaBDE) |
214-604-9 |
1163-19-5 |
PBT2 |
|
40 |
壬基酚 Phenol, 4-nonyl-, branched and linear covering all individual isomers with an alkyl chain of carbon number 9 and UVCB substances which include linear and branched alkyl chains with a carbon number of 9 |
—— |
—— |
EQC3 |
|
41 |
偶氮二甲酰胺 Diazene-1,2-dicarboxamide (C,C'-azodi(formamide)) |
204-650-8 |
123-77-3 |
EQC |
|
42 |
辛基酚聚醚-9 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated |
—— |
—— |
EQC |
|
43 |
乙二醇二乙醚 1,2-Diethoxyethane |
211-076-1 |
629-14-1 |
CMR |
|
44 |
甲基六氢苯酐、4-甲基六氢苯酐、甲基六氢化邻苯二甲酸酐、3-甲基六氢苯二甲酯酐 Hexahydromethylphathalic anhydride、Hexahydro-4-methylphathalic anhydride、Hexahydro-1-methylphathalic anhydride、Hexahydro-3-methylphathalic anhydride |
247-094-1、243-072-0、256-356-4、260-566-1 |
25550-51-0、19438-60-9、48122-14-1、57110-29-9 |
EQC |
|
45 |
六氢邻苯二甲酸酐 Cyclohexane-1,2-dicarboxylic anhydride |
201-604-9 |
85-42-7 |
EQC |
|
46 |
支链和直链1，2-苯二羧二戊酯 1,2-Benzenedicarboxylic acid, dipentylester, branched and linear |
284-032-2 |
84777-06-0 |
CMR |
|
47 |
邻苯二甲酸正戊基异戊基酯 N-pentyl-isopentylphtalate |
—— |
—— |
CMR |
|
48 |
全氟代十四酸 Heptacosafluorotetradecanoic acid |
206-803-4 |
|
PBT |
|
49 |
全氟十三酸 Pentacosafluorotridecanoic acid |
276-745-2 |
72629-94-8 |
PBT |
|
50 |
全氟十一烷酸 Henicosafluoroundecanoic acid |
218-165-4 |
2058-94-8 |
PBT |
|
51 |
全氟十二烷酸 Tricosafluorododecanoic acid |
206-203-2 |
307-55-1 |
PBT |
|
52 |
甲氧基乙酸 Methoxy acetic acid |
210-894-6 |
625-45-6 |
CMR |
|
53 |
邻苯二甲酸二异戊酯 Diisopentylphthalate |
210-088-4 |
605-50-5 |
CMR |
|
54 |
N,N-二甲基甲酰胺 |
200-679-5 |
|
CMR |
1.CMR：致癌、致突变、致生殖毒性
2. PBT：可持续性、生物可蓄积性和毒性
3.EQC：同等关注物质
更多详情参见：http://echa.europa.eu/view-article/-/journal_content/b5d76d7f-7b28-4081-bd5c-9500e01e1ab2
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